Kidney Transplant Research Today is a free monthly online journal that collates and summarizes the latest research about Kidney Transplant, including details on risks, prognosis, procedure, surgery, organ donation.

Morphological characteristics of spermatozoa before and after renal transplantation.

Xu LG, Shi SF, Qi XP, Huang XF, Xu HM, Song QZ, Wang XH, Shao ZF, Zhang JR

Renal Transplantation Center, 117th Hospital of PLA, Hangzhou 310013, China. xulonggen@sina.com.cn

AIM: To investigate the changes of the spermatozoa ultrastructures before and after renal transplantation in uremic patients. METHODS: The sperm of five uremic patients before and after transplantation and four healthy volunteers were collected and examined by scanning electron microscopy. RESULTS: Abnormal spermatozoa were found in patients pre-transplantation; abnormalities included deletion of the acrosome, absence of the postacrosomal and postnuclear ring, dumbbell-like changes of the head, tail curling, and absence of the mitochondrial sheath in the mid-segment. After renal transplantation, most of the spermatozoa became normal. CONCLUSION: There are many abnormalities with regard to the appearance and structure of the head, acrosome, mitochondria and tail of the spermatozoa in uremic patients. The majority of the spermatozoa returned to normal after renal transplantation, but a few still presented some abnormalities possibly relating to the administration of immunosuppressants.

Published 1 February 2005 in Asian J Androl, 7(1): 81-5.
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