Kidney Transplant Research Today is a free monthly online journal that collates and summarizes the latest research about Kidney Transplant, including details on risks, prognosis, procedure, surgery, organ donation.

Evaluation of renal function in transplantation.

Poggio ED, Batty DS, Flechner SM

Department of Nephrology and Hypertension and Transplant Center, Cleveland Clinic, Cleveland, OH 44195, USA. poggioe@ccf.org

Kidney dysfunction causes a myriad of adverse influences on posttransplant outcomes necessitating accurate assessment of kidney function for patient management. This evaluation assists in guiding treatment decisions, with the ultimate aim of allaying renal function decline. In clinical practice, renal function is typically estimated from serum creatinine levels, creatinine-based estimation equations or creatinine clearance; however, each of these methods has demonstrated limitations when used in the kidney transplant setting. Equally important is the emerging recognition of the incidence and impact of kidney dysfunction in recipients of nonrenal solid organ transplantation. The performance of commonly used estimation equations and methods for measuring kidney function in renal and liver transplant patients are overviewed here along with their potential roles in clinical transplantation.

Published 1 August 2007 in Transplantation, 84(2): 131-6.
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